JigCell Run Manager (JC-RM): a tool for managing large sets of biochemical model parametrizations
Layne T. Watson, Clifford Shaffer
Most biomolecular reaction modeling tools allow users to build models with a single list of parameter values. However, a common scenario involves different parameterizations of the model to account for the results of related experiments, for example, to define the phenotypes for a variety of mutations (gene knockout, over expression, etc.) of a specific biochemical network. This scenario is not well supported by existing model editors, forcing the user to manually generate, store, and maintain many variations of the same model.
- Date of publication:
- BMC Systems Biology
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